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食用小麦与掉发间的关联

[日期:2012-08-31] 来源:網絡轉載  作者:佚名 [字体: ]

这是一篇探讨食用麦类制品与掉发之间的关连性研究,其中与PCOS与SHBG做连结,也提出男性过早掉发的原因之可能

一直以来,我们都被灌输麦类,特别是全麦,对我们只有好处没有坏处这样的观念。不过麦类只有好处这件事,实际上只有一半的事实。确实有一些麦类是有益的,像是
藜麦,小米与乔麦(quinoa, millet and buckwheat)。但就算是全麦类,这些在西方国家中广泛被食用的食物,对健康与头发可能会造成问题的(统计上与肥胖跟MPB有很高的发生率)。这些麦类包括,小麦,大麦,黑麦,燕麦(由于处理过程中小麦遭到交叉污染)(wheat, barley, rye, and oats)。

这是因为谷蛋白的是由gliadinglutenin的蛋白质组成,会造成很未知的免疫系统的不良反应,以过敏发炎,慢性疲劳与忧郁等多种征状显现。我们一定想问,这跟掉发又有什么关系?

这个问题的答案和一种在女性中被诊断出的疾病,多囊性卵巢症(PCOS)有关。PCOS与内分泌失调有多种关联,其中最著名的是妇女多毛症(体毛生长),雄激素性落发与胰岛素阻抗。现在的研究指出男性相等于PCOS的症状,也普遍存在,这是由于一些关键基因与饮食、环境因子交互作用而产生。胰岛素抗阻(Insulin resistance),是PCOS形成的主要原因之一,它会导致女性有较高的雄性荷尔蒙,以及男性有较高的动情素跟DHT。治疗男性中的胰岛素阻抗才能使不正常的高DHT/T的比例与低T/动情素的比例趋于正常。

文献探讨中很有趣地显示,有PCOS的这些人,87%对小麦蛋白有某种程度的敏感或过敏。在这些状况下食用麦类会对胰岛素管理造成很大的迫害,进而造成血清中葡萄糖与胰岛素持续的升高。此外,摄取麦类可能会增加自由基并且降低营养物的吸收,易造成潜在的缺乏症与健康问题(就可能包含了头发问题)

虽然停止摄取麦类不可能治好秃发,但对秃发发展进程却有帮助。这几年来我们收到一些依我们建议而停止麦类摄取的女性(有一些并没有诊断有PCOS)的非正式回报,她们说,在停止麦类的食用后几天,发现掉发量有戏剧性地减少。因为这种疾病(PCOS)与雄性基因的存在有关连,所以停止麦类摄取可能非常有益于治疗男性与女性的掉发。

PCOS的女性与男性中常常会发现低浓度的SHBG。事实证明,有MPB的年轻男性比控制组有明显低的SHBGSHBG浓度会因着使用绿茶萃取物,健康地且轻而易举地被提高。同时使用绿茶与黄豆或绿茶与红茶萃取,在动物实验中被证实可降低血清中的DHT

过早雄性秃掉发与胰岛素抗阻,男性出现相当多囊卵巢症有关?
 

摘要
背景:多囊卵巢综合征(PCOS),最常见的内分泌病,估计发病率在女性为 5-10%,特点是荷尔蒙和代谢失调的多基因常染色体显性遗传性状。症状的复杂性和遗传基础上开始了假设的存在相当于男性的PCOS患者。30岁以前过早掉发,暗示(可能)男性出现PCOS症状。
目标:目的是确认较低水平的卵泡刺激素(FSH)和性荷尔蒙结合球蛋白(SHBG)或较高游离雄性素指标在男子过早秃顶与胰岛素敏感性降低的关连性。
病人/方法:本研究包括30个30岁之前的男性出现过早掉发(定义为 3期或以上的掉发分期)。比较来自256男性年龄在20-40岁的捷克人。
结论:研究结果是一致的假设,即至少有一部份的男性雄激素性脱发可能与过早被视为男性相当于多囊卵巢综合症的妇女。这些过早秃顶男人代表了具有萄糖耐量异常的或第二型糖尿病的风险。

原文 
Premature androgenic alopecia and insulin resistance. Male equivalent of polycystic ovary syndrome?
Starka L, Duskova M, Cermakova I, Vrbikova J, Hill M.
Institute of Endocrinology, Narodni 8, CZ 116 94 Prague 1, Czech Republic.

Abstract
BACKGROUND: Polycystic ovary syndrome (PCOS), the most frequent endocrinopathy in women with estimated prevalence of 5-10 %, is characterised by a hormonal and metabolic imbalance of polygene autosomal trait. The complexity of symptoms and genetic base started up the hypothesis on the existence of male equivalent of PCOS. Precocious loss of hair before 30 years of age was suggested as one of the male symptoms of this syndrome. OBJECTIVES: The aim was to confirm the association of lower levels of follicle stimulating hormone (FSH) and sexual hormone binding globulin (SHBG) or higher free androgen index (FAI) in premature balding men with a reduced insulin sensitivity. PATIENTS/METHODS: The study included 30 men with premature hair loss (defined as grade 3 vertex or more on the alopecia classification scale by Hamilton with Norwood modification) starting before 30 years of age. The hormonal values of the investigated group were compared with those regarded as normal reference values obtained in a group of 256 males in the age of 20-40 years during the Czech population study of iodine deficiency. In all men with premature baldness besides hormonal level determinations insulin tolerance test was carried out. RESULTS: The observed group was divided into two subgroups. The first one showed similar hormonal changes as women with PCOS, namely subnormal SHBG, FSH or increased FAI. The other had either no anomalies in steroid spectrum or only lower SHBG. The groups did not differ either in BMI or in age. The group with hormonal profile resembling that of women with PCOS, showed significantly higher insulin resistance than the group without these changes. CONCLUSIONS: The findings are consistent with the hypothesis that at least a part of the men with premature androgenic alopecia could be considered as a male equivalent of the polycystic ovary syndrome of the women. These premature balding men represent a risk group for the development of impaired glucose tolerance or diabetes mellitus type 2.

转载自 董哥的家 - iwanthair's blog

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